Topiramate is an anticonvulsant drug which is prescribed for treatment of chronic lower back pain & epilepsy. It is also most commonly indicated for preventing migraines so as to decrease frequency of attacks. This medicine shows bioavailability of about 80% with protein binding ability of up to 41%. It is consumed orally and gets rapidly absorbed after ingestion. This compound is excreted in urine after elimination half life of up to 25 hours. Topiramate appears as white to off-white colored powder which shows solubility in methanol & dichloromethane. It has molecular formula C12H21NO8S with molar mass of 339.363 g/mol.
IUPAC NAME - 2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
Cas No 97240-79-4 Molecular Formula C12H21NO8S Average mass 339.362 Da Monoisotopic mass 339.098785 Da